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Sr System Engineer

Santa Clara, CA 95050

Posted: 03/25/2024 Job Number: 71821 Pay Rate: $65.00 - $70.00

Job Description

THE POSITION:
Our client is developing new technologies to make genetic testing easy, reliable, and affordable. We are creating technologies and workflows that can be used to improve the lives of people in a wide variety of applications including the timely screening of newborns for diseases and the diagnosis of cancers and infectious diseases.


They are looking for a motivated and team-oriented individual who is passionate about revolutionizing sequencing technology. As a Senior System Engineer, you will learn how to use the new sequencing platform and help to develop the final operating protocols. The candidate will help design and perform wet-lab experiments to further develop the sequencing prototype instrument. The candidate will work with his/her manager and team members to interpret the experimental results and design future experiments. The candidate must be self-motivated and able to work well in a multidisciplinary team environment.


ESSENTIAL FUNCTIONS:
  • Become an expert on the operation of the Single Molecule Sequencing Platform.
  • Perform a variety of sample prep, library, or sequencing and sequencing related experiments on a daily basis, help to analyze and interpret the data.
  • General support of diverse research and development activities.
  • Contribute to the platform verification team as a member by executing, analyzing, and interpreting the results of platform verification studies.
  • Assist in preparing information for verification documentation and verification reviews.
  • Perform all work using best laboratory practices and maintain a well-organized and concise record of work performed and progress made.
  • Analyze data, derive conclusions, document findings, write SOPs and prepare reports for sharing within and between R&D groups
  • Setup strong experimental designs while working independently.
  • Troubleshoot instrument failures and seek out specialized help as needed.
     
RESPONSIBILITIES:
  • Develop and deploy a wide range of technologies, including sample extraction, library prep, and sequencing.
  • Develop, execute, and document test cases for verification and validation. Ensures complete and comprehensive coverage of requirements in the test campaigns.
  • Perform system integration and testing activities and verify system performance through simulation, tests, and measurements. Assess results for applicability, validity, and conformance to product requirements.
  • Work independently with general management direction to drive product development and collaborations to identify opportunities for continuous improvement.
  • Keep supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas.
     
MINIMUM QUALIFICATIONS:
  • B.S. degree in the chemistry/science/engineering required and 5-7 years of experience or M.S. degree with 4-6 years. PhD with 3+ year related experience. (Candidates with hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing are encouraged to apply and we can level the position to the experience.)
  • Previous laboratory experience required.
  • Familiarity with MATLAB, GIT, Python or similar tools for data analysis and/or automation.
  • Previous experience with prototype instruments or single molecule systems is desirable.
  • Excellent written and oral communication skills are essential.
  • Demonstrated ability to work well in teams and across scientific disciplines is essential.
  • The candidate should be passionate, self-motivated, and possess a strong desire to acquire on-the-job training.

IDEAL CANDIDATE:
  • Experience with a variety of laboratory devices and instrumentation, including PCR and automation.
  • In addition to impeccable technical skills, successful candidates possess strong organizational, communication and team skills, and thrive in a fast-paced environment
  • Resourceful and flexible; Fast learner and a self-starter; hard-working
  • Adept at planning, prioritizing, multi-tasking, organizing and following through, while remaining highly energetic and focused;
  • Straightforward, self-driven, and trustworthy;
  • An individual with experience in biotechnology or medical device development;
  • Strong understanding of DNA & molecular Biology
  • Breadth of knowledge / cross-disciplinary
  • 3+ years hands-on experience with DNA sequencing such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing.
  • Knowledge in all phases of NGS workflow such as nucleic acid chemistry, and primer design technologies for gene targets is highly desirable.
  • Proven hands-on troubleshooting experience and skills in wet bench workflows on NGS platform.
  • Experience with statistical tools (e.g. Python/JMP for regression analysis, ANOVA) and
  • Design of Experiments methodology, application of statistical process control is essential.
  • Experience in implementing workflow on semiconductor-based sensing devices or microfluidic devices is desirable.
  • Knowledge in surface chemistry is also desirable
  • Strong analytical, problem-solving, communication, and interpersonal skills and a fast learner.
     
DESIRED QUALITIES:
  • Anticipates needs and problems while creating solutions. Not always instruction-based
  • Demonstrates a sense of urgency, contagious optimism and a?can do attitude
  • Is curious, inquisitive, innovative, never satisfied with the status quo
  • Greets challenge and change as opportunity
  • Collaborates with others and strong orientation towards teamwork
EEO Statement Apollo Professional Solutions, Inc. is an equal opportunity employer. We provide equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, marital status, age, national origin, ancestry, disability status, medical condition, pregnancy, genetic information, protected veteran status, gender, sexual orientation, gender identity or expression, or any other status or characteristic protected under federal, state, or local law.

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